New Research Shows Experimental Treatment Working For Advanced Cancer Cases

The study is thought to be the largest breast cancer treatment trial ever

After nine years, 94% of both groups were still alive and about 84% were alive without signs of cancer, meaning that the chemo made no difference.

The experiment led to "complete durable regression" of the cancer that had spread to Judy Perkins' liver, the team said, writing in the journal Nature Medicine. According to a report by The Guardian, she was 49 when she was given a few months to live after seven types of chemotherapy failed and she had developed tumours the size of fists in her liver.

More than 20,000 women in the United Kingdom are diagnosed with hormone-receptor positive, HER2-negative, node-negative breast cancer annually.

However, the results of the TAILORx trial show that only 30% of women with this particular form of early-stage breast cancer benefit from the treatment.

The New England Journal of Medicine published a study on Sunday that examined a popular genetic test that estimated cancer risk based on nearly two dozen genes linked with the recurrence of breast cancer, according to CNN. By continuing the personalized assessment of an individual's cancer recurrence risk, oncologists can more effectively determine specifically-tailored treatments based on that patient's genomic results.

But Drs Sparano and Mayer added a note of caution: The data indicated that some women 50 and younger might benefit from chemo even if gene-test results suggested otherwise. Under-50s with a score of up to 15 can also be spared the treatment. The results suggest that nearly 70 per cent breast cancer patients can avoid chemotherapy. Another, more sinister, aspect to these headlines is the potential to fuel myths and conspiracy theories about the effectiveness of chemotherapy. "Practically speaking, this means that thousands of women will be able to avoid chemotherapy, with all of its side effects, while still achieving excellent long-term outcomes", said ASCO expert Dr Harold Burstein.

There is no known cure for breast cancer patients whose disease has spread so widely.

Rachel Rawson, clinical nurse specialist at Breast Cancer Care, said: "This life-changing breakthrough is absolutely wonderful news as it could liberate thousands of women from the agony of chemotherapy".

Treatment is a personal decision and that's why it's important for patients to discuss their options with their doctor, Figueredo said.

It saves lives, but side-effects of the toxic drugs range from vomiting, fatigue and infertility to permanent nerve pain.

The success of this case has raised hopes that the therapy could also be used to treat advanced ovarian and prostate cancers. The trial is in its early stages - with a projected closing date for the study pencilled in for 2023, it could be a while before medics can assume the new method is safe. So, we used to say for that group of women, in terms of chemotherapy, "better safe than sorry".

In addition, a recent study says chemo does not improve survival, that most women can be safely treated with just surgery and hormone blockers.

For women whose tumors received a low Oncotype DX score (1-10) or a high one (26 to 100), decisions on post-surgical chemotherapy have been clear. "I had given up fighting", Perkins said.

"Because this is a huge study". "But we need to be precise on when to use it and who to recommend it to".

FILE - In this January 28, 2003, file photo, Rep. Stephanie Stuckey Benfield, D-Decatur, promotes the breast cancer prevention stamp from the well on the floor of the House in Atlanta.

Researchers took a small sample of Ms Perkins' tumour and studied the DNA mutations in it.

Related News:



Most liked

Belmont Stakes: Justify draws No
Hofburg, who is trained by William I Mott and ridden by Irad Ortiz, drew the fourth post and is the second choice at 9-2. Baffert is not a fan of the inside post for his horses, no matter what the race.

Celtics Among Teams LeBron James Will Meet With In Free Agency
Warriors stars Steph Curry and Kevin Durant also took questions from reporters about what they expected in Game 3 . Kerr also lauded the Eagles for being what he called "fantastic citizens in their own community".

Pentagon warns Assad against attack on Kurdish forces
The official, who spoke on condition of anonymity because he was not authorized to speak to the media, gave no further details. The agreement envisages Iranian forces pulling out from the entire area and Syrian rebels there surrendering heavy weapons.

NKorea letter diplomacy is a throwback to a different era
Chol, together with his delegation from Pyongyang, touched down at the JFK International Airport. "It's a process. That would not be desirable for Pyongyang given its desire for a summit with Trump as soon as possible.