How High Doses of Ibuprofen May Impact Male Infertility

Popping ibuprofen could make your balls shrivel

However, for men, it could compromise their ability to procreate, a new study suggests. Unfortunately, a new study says that ibuprofen can actually reduce fertility rates in men.

Ibuprofen is a popular over-the-counter drug used to alleviate pain, fever and inflammation - especially in cases of painful menstrual periods, migraines and rheumatoid arthritis.

The researchers found that, compared with the placebo group, the men who took ibuprofen experienced a 23 percent increase in levels of luteinizing hormone (LH) - a hormone that's secreted by the pituitary gland and stimulates the production of testosterone - after two weeks.

The authors concluded that "we report a univocal depression of important aspects of testicular function, including testosterone production, after use of over-the-counter ibuprofen".

Men who dream of starting a family may want to pass on the ibuprofen the next time they have a headache. This indicates that they had developed a condition called "compensated hypogonadism", which happens when testosterone production is reduced, but the body is able to compensate by increasing LH levels, the researchers said.

This led, they said, to compensated hypogonadism, a condition linked to reproductive and other health problems normally found in elderly men.

Advil and Motrin are two brand names for ibuprofen.

Previous research by the team, which focused on pregnant women, had found that the use of Paracetamol and Ibuprofen during pregnancy affected the testicles of male babies. Professional athletes, however, do tend to take ibuprofen frequently, so this research could spark a serious look into the way those under physical strain treat their aches and pains.

It is known to increase the risk of heart attacks and stroke if taken regularly in high doses for a long time. The study shows that ibuprofen use results in selective transcriptional repression of endocrine cells in the human testis.

Thankfully, the 31 volunteers recovered after they stopped taking the pills.

"These are the first-ever results to show a link between ibuprofen and fertility", Bernard Jegou, a senior scientist at the French Medical Research Council and the school of public health at the Research Institute for Environmental and Occupational Health in France, who coordinated the study, told The Telegraph.

The findings are certainly significant, as the 1,200mg of ibuprofen given to the participants each day is far below the suggested daily maximum of 3,200mg per day.

Related News:

  • AMD's 2018 roadmap: Desktop APUs in February, second-generation Ryzen in April

    AMD's 2018 roadmap: Desktop APUs in February, second-generation Ryzen in April

    Why? AMD hopes to carry on the momentum initiated with the Ryzen chips launched in 2017 with the second gen versions of the same. These are simply the Ryzen "amateur" parts with the manageability features not turned off, but they are still very important.
    First joint Intel and AMD chip revealed

    First joint Intel and AMD chip revealed

    And that premium placement means they're going to go into high-spec laptops which demand an equally high price. Intel and AMD have finally shown us the first product from their partnership which was announced a year ago .
    'The Mayor' canceled at ABC as a bad timeslot claims another victim

    'The Mayor' canceled at ABC as a bad timeslot claims another victim

    Check out our list of midseason premieres to find a new show or lament about what else has been axed with our cancellation guide. ABC has no plans to air the remaining four episodes of season one, despite ordering three additional backup scripts in December.
  • JFK woes 'unacceptable — Airport agency head

    JFK woes 'unacceptable — Airport agency head

    More delays have been added Sunday to the storm-related aftermath the already beleaguered airport is working to recover from. QUEENS -JFK is nearly back to normal - and that means long lines, delayed flights and thousands of frustrated passengers.

    Ford F-150 Diesel Revealed: 440 LB-FT Punch, 30 MPG Efficiency

    For now Ford has only one competitor when it comes to the half-ton diesel game, and that's the Ram EcoDiesel. It's the sixth engine choice for F-150 customers. - Customers can order a diesel F-150 starting this month.

    Nikki Haley Defends Trump Tweet Comparing Nuclear Button Sizes With North Korea

    The DPRK accepted it without any change of the dialogue venue and time that South Korea had proposed. The Japanese government plans to reject any additional demands by South Korea on the topic.
  • Does Leaked Ewan McGregor Photo Confirm The Obi-Wan 'Star Wars' Spin-Off?

    Does Leaked Ewan McGregor Photo Confirm The Obi-Wan 'Star Wars' Spin-Off?

    Last year, Lucasfilm president Kathleen Kennedy teased that the next Star Wars spin-off would be confirmed by Summer 2017 . EWAN McGregor has sent Star Wars fans into a frenzy with a hot and sweaty workout pic.
    One Google Home Device Is Sold Every Second: Google

    One Google Home Device Is Sold Every Second: Google

    A year ago in November, Google rolled out an update, which allows the users to use Home speakers as intercom systems in the house. Devices from Amazon and Google are the clear leaders in the smart speaker category with their respective Echo and Home products.
    DJI Osmo Mobile 2 packs phone stabilization for $129

    DJI Osmo Mobile 2 packs phone stabilization for $129

    According to DJI, the Ronin-S supports Canon 5D, Panasonic GH and Sony Alpha systems with a wide combinations of lenses. Unlike the first generation, the Osmo Mobile 2 is lighter in construction and comes with fewer screws.
  • HTC Vive Pro revealed alongside Vive Wireless Adaptor

    HTC Vive Pro revealed alongside Vive Wireless Adaptor

    Please whitelist us in your adblocker software so that we can continue to provide quality content. The Pro's updated headstrap includes a sizing dial for a more balanced fit on the head.
    Charred body of technician found in Kanjurmarg studio fire

    Charred body of technician found in Kanjurmarg studio fire

    The studio is located at Kajurmarg in Mumbai where two TV serials were being shot- Bepanaah and Haasil- at that time. Similarly, 12 people were killed on December 18 after a fire broke out at a snack shop in Mumbai's Saki Naka area.
    Grigor Dimitrov Leaps Over Net to Help Injured Opponent Kyle Edmund

    Grigor Dimitrov Leaps Over Net to Help Injured Opponent Kyle Edmund

    While Dimitrov continues to impress, his opponent in the quarter-final faced a major injury scare in the third set. Dimitrov set up a tantalising clash with Kyrgios after outlasting Edmund .


Most liked

Google announces Google Pay to replace Android Pay and Google Wallet
The launch of Google Pay is an attempt to create some brand cohesion, but there's no clarity on how long that might take, he said. Through Google Pay, it is possible to send and receive money from/to your friends/colleagues/family apart from shopping payments.

Princess Charlotte Photos Show Adorable Tot Off to Nursery School
In the pictures, the fourth in line to the throne is wearing a coat and scarf and what appears to be a rucksack. The nursery school, founded in 1964, is housed in a church hall just a short walk from Kensington Palace.

Man Calls 911 To Report Himself For Drunk Driving
He reported himself to the police and told the dispatcher that he was driving drunk, and needed to be pulled over. The Polk County Sheriff's Office posted the 911 call on Facebook using the hashtag "Hello 9-1-1 I'm hammered".

Jaguars, Bortles struggle, but get past Bills in AFC wild card
But their visit to Pittsburgh in week five gave a first real glimpse of what this Jacksonville team could become. Buffalo's Tyrod Taylor is 13 of 26 for 98 yards while LeSean McCoy has 15 carries for 66 yards.